High-throughput system to study decision-making across multiple levels of reward and cost
type: Dataset
creator: Ibanez-Alcala, Rodrigo J
  type: Person
  given name: Rodrigo J
  family name: Ibanez-Alcala
  affiliation: University of Texas at El Paso
creator: Beck, Dirk W.
  type: Person
  given name: Dirk W.
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  affiliation: University of Texas at El Paso
creator: Salcido, Alexis A.
  type: Person
  given name: Alexis A.
  family name: Salcido
  affiliation: University of Texas at El Paso
creator: Villarreal Rodriguez, Kryssia
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  given name: Kryssia
  family name: Villarreal Rodriguez
  affiliation: University of Texas at El Paso
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  type: Person
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  affiliation: University of Texas at El Paso
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  type: Person
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  type: Person
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  affiliation: University of Texas at El Paso
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  affiliation: University of Texas at El Paso
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  affiliation: University of Texas at El Paso
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  affiliation: University of Texas at El Paso
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  type: Person
  given name: Austin J
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  affiliation: University of Texas at El Paso
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  type: Person
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  family name: Chavez
  affiliation: University of Texas at El Paso
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  family name: Hernández
  affiliation: University of Texas at El Paso
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  type: Person
  given name: Felix
  family name: Ramirez
  affiliation: University of Texas at El Paso
creator: Ordonez, Miguel
  type: Person
  given name: Miguel
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  affiliation: University of Texas at El Paso
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  type: Person
  given name: Jonathan
  family name: Lopez
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  affiliation: University of Texas at El Paso
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  type: Person
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  family name: Medina
  affiliation: University of Texas at El Paso
creator: Ordonez, Pablo
  type: Person
  given name: Pablo
  family name: Ordonez
  affiliation: University of Texas at El Paso
creator: Martinez, Gustavo
  type: Person
  given name: Gustavo
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  affiliation: University of Texas at El Paso
creator: Szafer Braun, Dana
  type: Organization
  parent organization: University of Texas at El Paso
creator: O'Dell, Laura E.
  type: Person
  given name: Laura E.
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creator: Moschak, Travis M.
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  family name: Moschak
creator: Goosens, Ki A
  type: Person
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creator: Friedman, Alexander
  type: Person
  given name: Alexander
  family name: Friedman
  affiliation: University of Texas at El Paso
author: Ibanez-Alcala, Rodrigo J
  type: Person
  given name: Rodrigo J
  family name: Ibanez-Alcala
  affiliation: University of Texas at El Paso
author: Beck, Dirk W.
  type: Person
  given name: Dirk W.
  family name: Beck
  affiliation: University of Texas at El Paso
author: Salcido, Alexis A.
  type: Person
  given name: Alexis A.
  family name: Salcido
  affiliation: University of Texas at El Paso
author: Villarreal Rodriguez, Kryssia
  type: Person
  given name: Kryssia
  family name: Villarreal Rodriguez
  affiliation: University of Texas at El Paso
author: Davila, Luis D
  type: Person
  given name: Luis D
  family name: Davila
  affiliation: University of Texas at El Paso
author: Drammis, Sabrina M.
  type: Person
  given name: Sabrina M.
  family name: Drammis
  affiliation: University of Texas at El Paso
author: Giri, Atanu
  type: Person
  given name: Atanu
  family name: Giri
  affiliation: University of Texas at El Paso
author: Heaton, Cory N.
  type: Person
  given name: Cory N.
  family name: Heaton
  affiliation: University of Texas at El Paso
author: Rakocevic, Lara I.
author: Hossain, Safa B.
author: Reyes, Neftali F.
author: Zhang, Marie
author: Batson, Serina A.
author: Macias, Andrea Y.
author: Umashankar Beck, Shreeya
author: Negishi, Kenichiro
author: Joshi, Arnav
author: Franco, Austin J
author: Chavez, Sarah A
author: Hernández, Bianca
author: Ramirez, Felix
author: Ordonez, Miguel
author: Lopez, Jonathan
author: Armenta, Abril
author: Quintanar, Odalys
author: Medina, Fernanda
author: Ordonez, Pablo
author: Martinez, Gustavo
author: Szafer Braun, Dana
author: O'Dell, Laura E.
author: Moschak, Travis M.
author: Goosens, Ki A
author: Friedman, Alexander
date published: 2023-06-02
date modified: 2024-02-07
version: 5
description: We designed a system to study decision-making in rats: the Reward-Cost in Rodent Decision-making (RECORD) system. RECORD allows for the creation of a decision-making task battery which leverages natural behaviors in rodents such as searching for food or avoiding threats without the need for food-deprivation. RECORD has three components: 3D-printed configurable arenas, custom electronic hardware, and software for databasing, analysis, and computational modeling. RECORD is fully automated and high throughput, which facilitates the longitudinal study of large cohorts of animals, as well as being cost-effective and quick to build. We validate the ability of RECORD to assess decision-making through experiments comparing individual and sex differences in various cost-benefit conflict tasks. We demonstrate how alcohol, oxycodone, and gut hormone ghrelin manipulations alter decision-making. Using modeling we interpret differences in individual psychometric functions. RECORD measures decision-making functions in rodents similar to those observed in humans, integral to translational studies on psychiatric disorders.
keywords: Medicine, Health and Life Sciences
keywords: Decision Making
keywords: Approach Avoid
keywords: Cost Benefit
keywords: Rat
keywords: high throughput
keywords: natural behavior
license: http://creativecommons.org/publicdomain/zero/1.0
included in data catalog: Harvard Dataverse

Rakocevic, Lara I.
type: Person
given name: Lara I.
family name: Rakocevic
affiliation: University of Texas at El Paso

Hossain, Safa B.
type: Person
given name: Safa B.
family name: Hossain
affiliation: University of Texas at El Paso

Reyes, Neftali F.
type: Person
given name: Neftali F.
family name: Reyes
affiliation: University of Texas at El Paso

Zhang, Marie
type: Person
given name: Marie
family name: Zhang
affiliation: University of Texas at El Paso

Batson, Serina A.
type: Person
given name: Serina A.
family name: Batson
affiliation: University of Texas at El Paso

Macias, Andrea Y.
type: Person
given name: Andrea Y.
family name: Macias
affiliation: University of Texas at El Paso

Umashankar Beck, Shreeya
type: Person
given name: Shreeya
family name: Umashankar Beck
affiliation: University of Texas at El Paso

Negishi, Kenichiro
type: Person
given name: Kenichiro
family name: Negishi
affiliation: University of Texas at El Paso

Joshi, Arnav
type: Person
given name: Arnav
family name: Joshi
affiliation: University of Texas at El Paso

Franco, Austin J
type: Person
given name: Austin J
family name: Franco
affiliation: University of Texas at El Paso

Chavez, Sarah A
type: Person
given name: Sarah A
family name: Chavez
affiliation: University of Texas at El Paso

Hernández, Bianca
type: Person
given name: Bianca
family name: Hernández
affiliation: University of Texas at El Paso

Ramirez, Felix
type: Person
given name: Felix
family name: Ramirez
affiliation: University of Texas at El Paso

Ordonez, Miguel
type: Person
given name: Miguel
family name: Ordonez
affiliation: University of Texas at El Paso

Lopez, Jonathan
type: Person
given name: Jonathan
family name: Lopez
affiliation: University of Texas at El Paso

Armenta, Abril
type: Person
given name: Abril
family name: Armenta
affiliation: University of Texas at El Paso

Quintanar, Odalys
type: Person
given name: Odalys
family name: Quintanar
affiliation: University of Texas at El Paso

Medina, Fernanda
type: Person
given name: Fernanda
family name: Medina
affiliation: University of Texas at El Paso

Ordonez, Pablo
type: Person
given name: Pablo
family name: Ordonez
affiliation: University of Texas at El Paso

Martinez, Gustavo
type: Person
given name: Gustavo
family name: Martinez
affiliation: University of Texas at El Paso

Szafer Braun, Dana
type: Organization
parent organization: University of Texas at El Paso

O'Dell, Laura E.
type: Person
given name: Laura E.
family name: O'Dell

Moschak, Travis M.
type: Person
given name: Travis M.
family name: Moschak

Goosens, Ki A
type: Person
given name: Ki A
family name: Goosens

Friedman, Alexander
type: Person
given name: Alexander
family name: Friedman
affiliation: University of Texas at El Paso

Harvard Dataverse
type: DataCatalog

Harvard Dataverse
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Harvard Dataverse
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