|
View: |
Part 1: Document Description
|
|
Citation |
|
|---|---|
|
Title: |
Replication Data for: Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults |
|
Identification Number: |
doi:10.7910/DVN/SAJJMX |
|
Distributor: |
Harvard Dataverse |
|
Date of Distribution: |
2025-11-17 |
|
Version: |
1 |
|
Bibliographic Citation: |
Abouyannis, Michael; Nyambura, Yvonne K.; Ngome, Samson; Riako, Debra; Musyoki, Jennifer; Muiruri, Charles; Orindi, Benedict; Else, Laura; Amara, Alieu; Dickinson, Laura; Clare, Rachel H.; Albulescu, Laura-Oana; Westhorpe, Adam P.; Kool, Jeroen; Adetifa, Ifedayo; Ndungu, Francis; FitzGerald, Richard; Khoo, Saye; Lalloo, David G.; Casewell, Nicholas R.; Hamaluba, Mainga, 2025, "Replication Data for: Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults", https://doi.org/10.7910/DVN/SAJJMX, Harvard Dataverse, V1 |
|
Citation |
|
|
Title: |
Replication Data for: Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults |
|
Identification Number: |
doi:10.7910/DVN/SAJJMX |
|
Authoring Entity: |
Abouyannis, Michael (Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool, UK; KEMRI-Wellcome Research Programme, Kilifi, Kenya) |
|
Nyambura, Yvonne K. (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Ngome, Samson (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Riako, Debra (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Musyoki, Jennifer (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Muiruri, Charles (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Orindi, Benedict (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
Else, Laura (Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK) |
|
|
Amara, Alieu (Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK) |
|
|
Dickinson, Laura (Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK) |
|
|
Clare, Rachel H. (Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool, UK) |
|
|
Albulescu, Laura-Oana (Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool, UK) |
|
|
Westhorpe, Adam P. (Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool, UK) |
|
|
Kool, Jeroen (Division of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV, Amsterdam, the Netherlands; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH, Amsterdam, the Netherlands) |
|
|
Adetifa, Ifedayo (KEMRI-Wellcome Research Programme, Kilifi, Kenya; Department of Infectious Diseases Epidemiology, London School of Hygiene & Tropical Medicine, London, UK) |
|
|
Ndungu, Francis (KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya) |
|
|
FitzGerald, Richard (NIHR Royal Liverpool and Broadgreen CRF, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK) |
|
|
Khoo, Saye (Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK; NIHR Royal Liverpool and Broadgreen CRF, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK) |
|
|
Lalloo, David G. (Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool, UK) |
|
|
Casewell, Nicholas R. (Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool, UK) |
|
|
Hamaluba, Mainga (KEMRI-Wellcome Research Programme, Kilifi, Kenya; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK) |
|
|
Distributor: |
Harvard Dataverse |
|
Access Authority: |
Abouyannis, Michael |
|
Access Authority: |
Data Governance Committee |
|
Depositor: |
Abouyannis, Michael |
|
Date of Deposit: |
2025-11-17 |
|
Holdings Information: |
https://doi.org/10.7910/DVN/SAJJMX |
|
Study Scope |
|
|
Keywords: |
Medicine, Health and Life Sciences |
|
Topic Classification: |
Phase 1 clinical trial, Snakebite, Envenoming, Unithiol |
|
Abstract: |
<p>This is a replication dataset for the manuscript titled: "Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults."</p> |
|
Kind of Data: |
Clinical Trial |
|
Kind of Data: |
Restricted Access |
|
Methodology and Processing |
|
|
Sources Statement |
|
|
Data Access |
|
|
Notes: |
<a href="http://creativecommons.org/licenses/by/4.0">CC BY 4.0</a> |
|
Other Study Description Materials |
|
|
Label: |
Abouyannis_TRUE1_data _readme.txt |
|
Notes: |
text/plain |
|
Label: |
Analyticalplan_BCA38_220117_v1.pdf |
|
Notes: |
application/pdf |
|
Label: |
Case Report Form Templates.zip |
|
Notes: |
application/zip |
|
Label: |
consort_dig.csv |
|
Notes: |
text/comma-separated-values |
|
Label: |
ICFs.zip |
|
Notes: |
application/zip |
|
Label: |
solic_ae.csv |
|
Notes: |
text/comma-separated-values |
|
Label: |
TRUE-1_protocol_v2.pdf |
|
Notes: |
application/pdf |
|
Label: |
unsolic_ae.csv |
|
Notes: |
text/comma-separated-values |